These include the following: 1) the ErbB receptor of EGF2 in non-small cell lung cancers 24, 2) signal transducer and activator of transcription 5 (STAT5) in immune cells stimulated by cytokines and/or growth factors 19, and 3) focal adhesion kinase (FAK), with which VHR plays a role in the formation and disassembly of focal adhesions 25. The gene discussed is DUSP3; the disease is non-small cell lung carcinoma.