In the Mexican (derivation) cohort, MMP28 was found significantly increased in IPF (6.8 ± 4.2 ng/ml) versus fibrotic non-IPF (4.0 ± 3.8 ng/ml) and healthy controls (1.7 ± 1.9 ng/ml) (ANOVA p<0.0001) (Fig 2, Blue). Here, MMP28 is linked to idiopathic interstitial pneumonia.