CTNNB1 and cancer: It has been reported that CK1ε promotes disease progression in some cancers through different targets such as MYC (MYC proto-oncogene, bHLH transcription factor), AKT (v-akt murine thymoma viral oncogene homolog), or β-catenin (catenin beta 1, also known as CTNNB1)11,14,16.