ITGA3 and metabolic dysfunction-associated steatotic liver disease: The expression levels of GPR56/ADGRG1, TLE3, CASZ1, FMN1, TIMP2, and ITGA3 increased with the progression of fibrosis, suggesting that the NAFLD liver undergoes fibrosis and acquires tumorigenic potential through coordinated changes in DNA methylation and the subsequent changes in gene expression levels in network 1.