CD14 and acute myeloid leukemia: First, several investigators have demonstrated that, although myeloid progenitors may be less permissive than other cell types, some expression of viral lytic genes is detectable at early times postinfection in various models of latency, including primary CD34+ HPCs; Kasumi-3 cells, a CD34+ myeloblastic cell line derived from a patient with acute myeloid leukemia (AML) (35), which is a tractable model for CMV latency and reactivation (27, 36, 37); and primary CD14+ peripheral blood mononuclear cells (11, 12, 36, –, 43).