SOD1 and early-onset autosomal dominant Alzheimer disease: In the polymer system, alteration of PMOXA-b-PDMS-b-PMOXA block lengths was used to tune permeability, ultimately producing SOD-encapsulated nanoreactors with optimized properties.48 These antioxidant-based nanoreactor systems are expected for application in prevention of age-associated pathologies, including cataracts,49 cancer, age-associated macular degeneration, and Alzheimer’s disease.