IL33 and atopic eczema: IL-33/ST2 signaling has been shown to potently invoke a T Helper 2 (Th2) immune response in inflammatory diseases and wound healing responses in several tissues, and has been implicated in many inflammatory and allergic diseases [7,8] including rheumatoid arthritis [9], atopic dermatitis [10], asthma [11], inflammatory bowel disease [12], and cardiovascular disease [13,14], among others.