SPRY4 and neoplasm: Four expression ratios were associated with AJCC stage of the tumour: The strongest such association by Spearman correlation was exhibited by the ratio CCAT1/ANRIL, which decreased with rising AJCC stage (p = 0.0072, Figure 7e), followed by CCAT1/MIR155HG (p = 0.0218), MALAT1/ANRIL (p = 0.0239) and SPRY4-IT1/ANRIL (p = 0.0337).