Kravtsova-Ivantsiv and colleagues [26] showed that KPC1 overexpression in a mouse xenograft tumour model derived from either the glioblastoma cell line (U87-MG cells) or the human breast cancer cell line (MDA-MB 231 cells) inhibits tumour growth via increased p50 generation. Here, NFKB1 is linked to breast carcinoma.