KEGG pathway analysis using 211 up- and 306 down-regulated DEGs revealed that cancer signaling in the complex subtype was mainly triggered by Wnt-Frizzled LRP5/6 and GPCR signaling, whereas glycan biosynthesis and metabolism are strongly blocked through down-regulation of PPAR signaling, beginning with CD36-FABP. The gene discussed is LRP5; the disease is cancer.