All PVH data except PVHTBR,20–40 > 2 (P = 0.072, r = 0.18) yielded strongly significant (P < 0.001) differences between molecular genetic groups and remained strongly significant in post hoc analysis of differences between IDH-mut (non-codel; codel) and IDH-wt gliomas. This evidence concerns the gene IDH1 and central nervous system cancer.