Sato et al. found that higher baseline CRP level was an independent risk factor for non-relapse mortality (NRM; HR: 6.21, P < 0.01), grade III–IV acute graft versus host disease (HR: 3.91, P = 0.03) and poor overall survival (HR: 3.27, P = 0.0018) [26]. The gene discussed is CRP; the disease is acute graft versus host disease.