It is well known that vascular endothelial growth factor A (VEGF-A) is a main mediator of angiogenesis and increased vascular permeability in retinal vascular disorders.1,2,3,4 The inhibition of vascular endothelial growth factor (VEGF) has been a key point in experimental and clinical studies under research. The gene discussed is VEGFA; the disease is retinal vascular disorder.