The intermediate expression levels of some pro-fibrotic genes at day 3 post injury, as well as the detection of few day 1 post injury pro-fibrotic genes in Vcam1+ subFAPs from mdx muscles, are likely accounted for by the presence of asynchronously activated FAPs at different stages of transition through a continuum of cell states, that might reflect the response to repeated cycles of degeneration-regeneration process typically observed in DMD muscles. The gene discussed is VCAM1; the disease is Duchenne muscular dystrophy.