FFAR2 and graft versus host disease: In contrast, the allogeneic [WT B6 → WT B6Ly5.2] and the [Gpr43−/− → WT B6Ly5.2] chimeras showed similar GVHD, while the [WT B6 Ly5.2 → Gpr43−/−] chimeras showed significantly more severe GVHD (P = 0.001).