Taken together, PEITC can diminish the ectopic xenograft tumor growth of GBM 8401 cells in tumor weights and volumes, which may be through the induction of apoptosis by the decrease of anti-apoptotic proteins MCL-1 and XIAP, and the increase of pro-apoptotic proteins caspase-3 and Bax. This evidence concerns the gene CASP3 and neoplasm.