XIAP degradation was induced and the NF-κB pathway was inhibited by 3-((decahydronaphthalen-6-yl)methyl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dione (RF-Id), which led to the cleavage of caspases 8, 9, 3, and 7, and blocked c-IAP2/XIAP interaction in in human glioblastoma U87MG and LN229 cells in vitro [24]. The gene discussed is XIAP; the disease is glioblastoma.