In addition, miR-155 showed low expression in pediatric BL, inversely associated with the downregulation of the nuclear interactor of ARF (ADP-ribosylation factor) and Mdm2 (murine double minute 2) (NIAM, the protein-coding transcript splice variant of TBRG1 locus), a protein with a tumor-suppressor function [111]. The gene discussed is TBRG1; the disease is Burkitt lymphoma.