KMT2A and acute myeloid leukemia: Emmrich et al. [65] observed that miR-582 and miR-9 are downregulated in t(8;21) AML; miR-500a and miR-192/194 are downregulated in AML with inv (16); and miR-181a, miR-1331, and miR-126 are downregulated while miR-187 is increased in MLL-rearranged AML.