What’s more, the expression levels of AXIN2, LGR5, SOX4 and MYC were positively correlated with that of SLCO4A1-AS1 in the 50 CRC sample tissues (Fig. 3j), which indicated that SLCO4A1-AS1 regulates Wnt/β-catenin signaling in CRC. This evidence concerns the gene AXIN2 and colorectal carcinoma.