However, PARK2 patients and heterozygous PARK2 mutation carriers are reported to exhibit higher rates of neuropsychiatric symptoms (e.g., depression, psychosis, panic attacks) than non-carriers [7, 54, 55], and there is a significant association between PARK2 heterozygosity and obsessive-compulsive disorder [56]. The gene discussed is PRKN; the disease is major depressive disorder.