PTPRD and rectal neoplasm: In multivariate analysis, both postulated deleterious PTPRT/PTPRD alterations and rectal tumors were independent factors associated with shorter PFS (HR, 3.33; 95% CI, 1.47–7.54; p = 0.0038 and HR, 2.56; 95% CI, 1.23–5.32; p = 0.0118, respectively).