In the current study, we demonstrate that a tripartite branched CPP incorporating the H-2Kb (SAPDTRPAP)- and HLA-A2 (STAPPAHGV)-restricted CTL epitopes from the MUC1 tumour antigen with the universal Th epitope tetanus toxoid (tetCD4) is internalised into DC in vitro, as well as in vivo. Here, MUC1 is linked to neoplasm.