The activation of metabolic rescue mechanisms, the differentiation of progenitor cell-like brain tumor initiating cells into non-tumorigenic cells, as well as the suppression of inflammatory response, are exerted through the activation of AMP-dependent kinase (AMPK) [7,10,13,14,35,36] and the downstream inhibition of mTOR [9,11,16]. This evidence concerns the gene MTOR and brain neoplasm.