DNMT1 and neoplasm: Recent work by Tang et al. [148] demonstrated that treatment of adipocytes alone with the DNMT inhibitor resulted in the re-expression of tumor suppressor genes (e.g., SUSD2, TFP12, GREM1, TRIM29), altered expression of EMT mediators (e.g., CDH1, CDH2, FN1, and SLUG), and diminished migrative and invasive properties of co-cultured EOC cells.