TUBB3 and congenital fibrosis of the extraocular muscles: Type 2 CFEOM is inherited in an autosomal recessive fashion, and the responsible gene is POX2A/ARIX, located on chromosome 11q13.1.[31] Type 3 CFEOM is inherited in an autosomal dominant fashion and is caused by a mutation in TUBB3 and KIF21A genes.