Data indicated that normal AA breast epithelial tissue adjacent to luminal A cancer expressed high levels of cytoplasmic Snail and Cat L compared to normal CA (which was mostly low to negative) and comparable to adjacent cancer, while normal AA breast epithelial tissue adjacent to TNBC expressed high levels of nuclear Snail and Cat L similar to TNBC tissue (Fig 6A and 6B). The gene discussed is CTSL; the disease is cancer.