SLC27A1 and age-related macular degeneration: The fact that dFatp overexpression increases LD size but not number also suggests that the role of FATP in LD expansion is conserved in Drosophila. Interestingly, retinal LD accumulation induced by FATP overexpression resembles one of the key hallmarks of AMD pathology; that is, the accumulation of lipids in RPCs and of drusen in Bruch’s membrane [32].