MFN1 and retinal degeneration: This is consistent with studies of flies with mitochondrial defects that cause high ROS levels in neurons, which demonstrated that removal of LDs by dFatp knockdown rescued retinal degeneration in sicily (Drosophila homolog of the human nuclear encoded mitochondrial gene NDUFAF6) and marf (Drosophila homolog of the mitochondrial fusion GTPases, Mitofusin 1 and 2) mutants and that ectopic expression of Bmm-lipase rescued photoreceptors in Aats-met mutants [9, 27].