TNFSF15 and inflammatory bowel disease: In contrast, under all stimulation conditions, soluble TNFSF15 was significantly increased in supernatants of cells from IBD protective allele homozygotes (immune complex p 6.56 x 10−4, intracellular poly(I:C) p 4.16 x 10−3, LPS p 3.42 x 10−3, Fig 3B).