Between June 2015 and May 2016, 80 patients were admitted to PMMH (this includes the 38 patients in Figure 1 who self-presented) and treated for HIV-associated CCM of whom 57 (71.3%) had a CD4 count ≤ 100 cells/mm3, 10 patients had a CD4 count > 100 cells/mm3 and 13 did not have their CD4 count recorded (Figure 3 and Table 3). The gene discussed is CD4; the disease is cerebral cavernous malformation.