Indeed, amyloid-β (Aβ) deposits and neurofibrillary tangles (NFTs) containing hyperphosphorylated Tau are classical histopathological features of AD that could also be observed in the retina of patients (Hart et al., 2016; Koronyo et al., 2017; Kusne et al., 2017; van Wijngaarden et al., 2017). This evidence concerns the gene MAPT and Alzheimer disease.