To assess whether the miRNA target genes obtained from IPA had an inverse expression to miR-217 level in MB, the expression levels of SIRT1, SMAD7, ROBO1, and FOXO3 gene were measured by qPCR in the HDMB03 cell line as well as in MB primary tumor by immunohistochemistry (IHC). This evidence concerns the gene FOXO3 and neoplasm.