Consistently, the promotion of GSK3β in miR-137 inhibitor-overexpressed cells also increased cell-invasive abilities compared to scramble vector pGIPZ transfectant, while knockdown of GSK3β completely abolished the increased BC invasion as compared to its empty vector pSuper transfectant (Figures 3C–3E; Figure S1C). This evidence concerns the gene GSK3B and breast cancer.