Based on our hypotheses, UCA1 may be an RNA regulator of CRC progression by controlling a ceRNA network, thus fostering the upregulation of ANLN, BIRC5, IPO7, KIF2A, and KIF23 in two ways: (1) by sponging miRNAs negatively regulating their expression, and (2) by directly binding the 3′-UTRs of mRNAs and protecting them from miRNA-mediated degradation. This evidence concerns the gene ANLN and colorectal carcinoma.