FXN and Friedreich ataxia: The increase of the FRDA FXN gene expression in vitro and in vivo by plTALEST10X-6-15 and plTALEST10X-8-15 improved mitochondrial activity in FRDA cells as indicated by the increased aconitase activity and regulation of PGC-1α and CAD65. 42Khonsari et al.15