Only rs12037376 (CDC42/WNT4), rs71575922 (SYNE1/ESR1), and rs77294520 (GREB1) associate with leiomyoma after correction for the number of tests (P < 0.05/19 = 2.6 × 10−3), with all three variants showing the same direction of effect for endometriosis and leiomyoma (logistic regression, Supplementary Data 7). This evidence concerns the gene ESR1 and endometriosis.