Our own work with aortic allografts, which is a model for chronic transplant vascular inflammation and fibrosis20,21, we demonstrated reduced vasculopathy and inflammation at 4 weeks follow-up in Ndst1−/− donor aortas implanted in WT BALB/c mice with normal Ndst1 expression (Ndst1+/+)19. The gene discussed is NDST1; the disease is vascular disorder.