Donor renal allografts from Ndst1−/− mice (on C57Bl/6 background) had significantly reduced overall pathology scores for early rejection when transplanted into BALB/c mice (Fig. 1C,D; P < 0.012) as well as significantly lower scores for cell infiltrates (Fig. 1E; P < 0.001), vasculitis (Fig. 2F; P < 0.0005), glomerulitis (Fig. 1G; P < 0.0001), peritubular capillaritis (Fig. 1H; P < 0.028), tubulitis (Fig. 1I; P < 0.0001), and mesangial matrix (Fig. 1J; P < 0.0096) when compared to saline-treated WT/B6 control grafts (Fig. 1D–J). Here, NDST1 is linked to vasculitis.