We also identified additional targets of mutant SRSF2-associated splicing alterations that are potentially involved in the development of myelodysplasia, including CASP8 and CDK10. Mutant SRSF2-associated exon skipping generated a prematurely terminated transcript (Supplementary Fig. 30), leading to a reduction of the canonical transcripts of the affected genes (Fig. 3d). The gene discussed is SRSF2; the disease is Myelodysplasia.