LRRK2 and Parkinson disease: Little is known about LRRK2 function in astrocytes, although post mortem PD brain analysis suggests that LRRK2 is indeed expressed in astrocytes (Dzamko et al., 2017), and overexpressing pathogenic mutation forms of LRRK2 impairs the lysosomal degradation capacity of primary mouse astrocytes (Henry et al., 2015).