F10 and deep vein thrombosis: The overall effect size showed that LMWH group was associated with a higher risk of DVT than factor Xa inhibitors for THR subjects (OR = 2.351, 95% CI = 1.040–5.314, P = 0.040) or TKR (OR = 1.827, 95% CI = 1.352–2.468, P < .001) (Fig. 3b; Additional file 1: Table S1).