In a previous case–control study, adjusting for number of lifetime blistering sunburns, ability to tan and hair colour did not appreciably alter the association between IGF‐I and melanoma risk.11 In addition, in our study we used a single measure of circulating IGF‐I concentration, but previous work has shown good reproducibility of circulating IGF‐I concentrations over three (intra‐class correlation (ICC) = 0.86),21 and five (ICC = 0.71) years.22 Finally, more than 90% of circulating IGF‐I is bound to IGF binding protein (IGFBP)‐323 and we did not measure IGFBPs in our study. The gene discussed is IGF1; the disease is melanoma.