In multivariate analyses, patients with abnormal CRP levels [>3 mg/L, N = 12 (40.4%)] were found to have higher depression scores than those with normal CRP levels in multivariate analyses (p = 0.035, OR = 1.067, 95% CI = 1.004–1.132). No significant association between CRP levels and antidepressant consumption was found. This evidence concerns the gene CRP and depressive disorder.