CEACAM5 and chronic kidney disease: The univariate analysis revealed several significant risk factors for cancer recurrence (Table 3), including blood transfusion, lower hemoglobin concentration, ASA class ≥3, chronic kidney disease, higher pretreatment CEA level, longer anaesthesia time, advanced cancer stage, specific pathologic findings (poor differentiation, mucinous or signet-ring histology, lymphovascular invasion, and perineural invasion), preoperative chemotherapy and/or radiotherapy, and postoperative chemotherapy or radiotherapy.