In contrast, in both the M5 and SW1417 models we observed only a low and non‐significant reduction in CXCR4+ CCF in the organs showing low sensitivity to T22‐GFP‐H6‐FdU, such as the primary tumor or LN Mets (Fig 6B and C, and Appendix Fig S8B and C). Here, CXCR4 is linked to neoplasm.