Moreover, T22‐GFP‐H6‐FdU treatment reduced also significantly (P = 0.027) the H‐score (percent and intensity of IHC stained and normalized by foci area) for CXCR4 expression in peri‐tumoral intravasated tumor emboli (0.017 ± 0.012), as compared to free oligo‐FdU‐treated (0.043 ± 0.010) or Buffer‐treated (0.038 ± 0.005) tumors (Fig 5E–G). Here, CXCR4 is linked to neoplasm.