Following, we analyzed the fraction of CXCR4+ cancer cells (CXCR4+ CCF) remaining in tumor tissue, along time, after a single 100 μg T22‐GFP‐H6‐FdU dose, as compared to free oligo‐FdU, using the SC CXCR4+ SW1417 CRC model in NOD/SCID mice. Here, CXCR4 is linked to cancer.