This is consistent with the very high level of CXCR4 expression in poor prognosis CRC (Kim et al, 2005, 2006; Schimanski et al, 2005) and other neoplasias (Fischer et al, 2008; Nimmagadda et al, 2009; van den Berg et al, 2011) in comparison with non‐tumor tissues. Here, CXCR4 is linked to colorectal carcinoma.