MiR-142-3p has been indicated as a novel regulator of Hsp70 expression in triptolide-induced pancreatic cancer cell death [136], and it has been reported that miR-1/miR-206 suppressed Hsp60 expression, contributing to glucose-mediated apoptosis via the MEK(extracellular signal-regulated kinase)-1/-2 pathway in cardiomyocytes [137]. The gene discussed is MAPK3; the disease is familial pancreatic carcinoma.