TEK and synovitis: As previously observed, serum levels of sVCAM-1 (816±297 ng/mL vs. 715±260 ng/mL, P = 0.045) and Tie-2 (16.3±7.3 ng/mL vs. 13.9±5.3 ng/mL, P = 0.041) were more likely to be increased in patients with relevant synovitis.