GPX4 and triple-A syndrome: In univariate analysis, the presence of the SELENOS rs34713741T, SEPP1 rs3877899A, or GPX4 rs713041T allele was related to a 30–61% increase in AIOD/PAD risk in the recessive or dominant model, while carriers of the SEPP1 rs3877899A allele had a 32% reduced risk of AAA (in the absence of PAD).