The presence of the GPX4rs713041TT/SELENOS rs34713741TT double homozygous genotype, compared to the occurrence of the rs713041CC+CT/rs34713741CC+CT genotype was related to 5.27-fold increase in the risk of AIOD in the case-control analysis (P = .0001), and 3.15-fold increase in the risk of this disease in relation to the risk of AAA (P = .009; Table 2). This evidence concerns the gene SELENOS and triple-A syndrome.