PTK2 and glomerular disorder: Multiple studies have provided evidence indicating that FAK is expressed in podocytes and is activated in many podocyte pathologies and glomerular diseases.4, 14 A previous study showed that integrin α5β3‐mediated FAK/PI3K pathway activation played a critical role in podocyte F‐actin cytoskeletal rearrangement.52 Our study demonstrated that integrin α6β4, another integrin family heterodimer, also activated FAK and induced actin filament rearrangements.