Although the association between NF1 and rhabdomyosarcoma is evident because of the accepted role of the NF1 gene in the differentiation of muscular cells, which explains a common pathogenetic mechanism, associations between neurofibromatosis and Wilms’ tumour or neuroblastoma are reported, but are not confirmed from a genetic and molecular point of view [7, 12]. Here, NF1 is linked to rhabdomyosarcoma.