TNF and type 2 diabetes mellitus: Table 1 and Figure 1 have additionally demonstrated the average levels of IL-6, TNF-α, and visfatin present within the GCF samples. In group 4, IL-6 and TNF-α are low but vistafin remains relatively high because the group 4 patients have been suffering from type 2 diabetes and chronic periodontitis, who had received 20 mg simvastatin as a lipid-lowering agent for 5–10 years.