In this context, the questions of whether this process is consistent between tumour cells and the apoptosis of islet β cells in diabetes, whether there is any association between the interaction of Par-4 with TERT and Par-4 nuclear translocation in islet β cell apoptosis, and if any relationship exists between Par-4 and Akt in the apoptosis of islet β cells remain to be investigated. Here, PAWR is linked to diabetes mellitus.