In another example, postnatal lethality caused by CRISPR/Cas9-mediated disruption of the Leber's congenital amaurosis (LCA)-associated gene potassium inwardly-rectifying channel, subfamily J, member 13 (Kcnj13) was circumvented by analyzing mosaic F0-generation mice. The gene discussed is KCNJ13; the disease is Leber congenital amaurosis.